There is currently a high volume of activity in the Particle Technology area (primarily supported through EPSRC's Manufacturing the Future Theme) that is strongly linked to industry. Many of the recent strategic investments have inflated and shifted the balance of the portfolio towards relatively high Technology Readiness Levels (TRLs) relevant to UK manufacturing.
Although there is potential to identify a number of new research challenges from the current portfolio, it is essential to focus on fundamental engineering research to ensure the long-term health of the area and to enable future impacts. Examples of these longer-term challenges may include the fundamental understanding of different, novel particulate systems and products, in relation to particle behaviour and process models (Evidence source 1). By the end of the Delivery Plan, EPSRC will work with the community to encourage focused grant applications that address fundamental challenges, so that the portfolio of research in this area will be appropriately balanced.
To ensure a balanced portfolio, we have considered this strategy alongside the broader chemical engineering portfolio (including the Complex Fluids and Rheology and Process Systems: Components and Integration research areas). Throughout the Delivery Plan period, we will work with the community to focus on collaboration across the chemistry and chemical engineering interface, identifying opportunities for multidisciplinary research that delivers against the Prosperity Outcomes and Ambitions in our Delivery Plan. Opportunities may exist to link to the Engineering Grand Challenge addressing Engineering across Length Scales, from Atoms to Applications.
The growing number of chemical engineering undergraduates, emanating from strong industrial demand, means student training remains highly relevant in this research area and across the wider chemical engineering portfolio (Evidence source 2). We will work with the chemical engineering community to explore and address any concerns over academic leadership and the balance of support across all career levels.
Highlights:
This research area increased significantly as a proportion of the EPSRC portfolio over the last Delivery Plan period, due to the recent investment in the Manufacturing the Future and the Physical Sciences Themes' call in Future Formulation of Complex Products; five of the seven funded grants contain Particle Technology research (Evidence source 3). These investments reflect the current importance of formulation science to industry and complement initiatives such as the National Formulation Centre, the Advanced Digital Design of Pharmaceutical Therapeutics Centre and the Innovate UK High Value Manufacturing strategy (Evidence source 4,5). These centres will enable UK businesses to collaborate with supply chain partners and academia to develop, prove, prototype and scale-up the next generation of formulated products. These innovation drivers have pushed particle technology research towards higher-TRL formulation-related research. There is also a need to refocus the area towards long-term fundamental engineering research challenges.
Particle Technology is seen as a mature subject area that is largely supported by industry. Many Small and Medium-Size Enterprises (SMEs) engaged in the formulation supply chain have their origins in spinouts from UK universities; this means they are supported by world-class expertise in particle design and particle processing (Evidence source 5).
Research in particle technology is core to many industrial processes and is dominated by industrial drivers (Evidence source 4,5). This area contributes to a number of leading UK industrial sectors including manufacturing, formulation, healthcare and pharmaceuticals (Evidence source 6) - a fact highlighted by the presence of a wide range of industrial partners on EPSRC investments (Evidence source 3).
Postgraduate training in this area has grown through the formation of a number of interlinked Centres for Doctoral Training (CDTs), which are strongly linked to industry. Training provisions through the Industrial Collaborative Awards in Science & Technology (CASE) and the Doctoral Training Partnership (DTP) schemes also benefit this area. These investments - concentrated in particular centres of excellence, with a small number distributed throughout the UK, and which maintained their number over the last Delivery Plan - broadly align with the growing industrial demand and increasing relevance of this research area. (Evidence source 2,3)
This area will draw on and contribute to other research areas and disciplines, such as Process Systems: Components and Integration, Complex Fluids and Rheology, Fluid Dynamics and Aerodynamics, and Microsystems. Research in this area strongly links to the Manufacturing the Future Challenge Theme.
This area has the potential to significantly contribute to the Productive Nation Outcome and will align to the Healthy Nation Outcome. It is particularly relevant to the following Ambitions:
P1: Introduce the next generation of innovative and disruptive technologies
This research area will play a critical role through fundamental understanding and manufacturing/scale-up of new particulate systems and products.
P2: Ensure affordable solutions for national needs
Research in this area has the potential to support the creation and manufacturing/scale-up of affordable medicines.
H4: Develop future therapeutic technologies
This research area will play a critical role through new approaches for the targeting, functionalisation, encapsulation and physical or chemical release of drugs.
- European Powder Metallurgy Association (EPMA), Vision 2025: Future Developments for the EU Powder Metallurgy Industry, (2015).
- ABPI, Bridging the Skills Gap in the Biopharmaceutical Industry (PDF), (2015).
- EPSRC portfolio data: size, investments, student numbers.
- Innovate UK, A Strategy for Innovation in the UK Chemistry-using Industries (PDF), (2013).
- Innovate UK, Realising the Potential for Formulation in the UK (PDF), (2013).
- EPSRC, The Importance of Engineering and Physical Sciences Research to Health and Life Sciences (PDF) ('the Maxwell review'), (2014).
Other sources:
- Community engagement with stakeholders and researchers.
- Learned Society Balancing Capability Workshop, (February 2016).
- Chemical Engineering Heads of Department meeting, (July 2016).