EPSRC UK National Mass Spectrometry Facility (NMSF)

Location of Facility

Swansea University Medical School, Park Campus, Swansea University, Swansea SA2 8PP

Capabilities and services provided

The EPSRC UK National Mass Spectrometry Facility (NMSF) provides comprehensive analytical mass spectrometry services. A suite of instrumentation is capable of analysing a very broad spectrum of chemical compounds, from small molecules to large biomolecules and polymers with high resolution and precise mass accuracy. Complex mixtures can be analysed using online chromatography, with both gas chromatography and high-performance liquid chromatography available, coupled to high-resolution accurate-mass mass spectrometers.

Ionisation techniques available:

Atmospheric Pressure Chemical Ionisation (APCI)
Atmospheric Pressure Solids Analysis (ASAP)
Chemical Ionisation (CI)
Electron Ionisation (EI)
Electrospray Ionisation (ESI)
Matrix-Assisted Laser Desorption Ionisation (MALDI)
MALDI Imaging (MSI)
nano-Electrospray Ionisation (nESI)

Chromatographic techniques available:

Gas Chromatography (GC)
High-Performance Liquid Chromatography (HPLC)

Services Provided:

Characterisation of both known and unknown compounds
Determination of elemental formulae from high-resolution accurate mass measurements
Structural information through tandem mass spectrometry
Quantitation of components within mixtures
Comprehensive training
Outreach visits to schools, universities and industry

The NMSF is able to provide hands on training in all aspects of mass spectrometry: sample preparation, instrument operation, instrument maintenance and data interpretation.

Enquiries from Academics and Industry are continually welcome.